—–Ua kope ʻia kēia ʻatikala maiMedpageToday
ʻO ka wehe ʻana i nā ovaries ʻelua ma mua o ka menopause e pili ana i ka nui o nā pilikia olakino maʻi a me ka hoʻemi ʻana i ka hana kino i nā makahiki ma hope, ʻoi aku hoʻi i nā wahine i hana ʻia ma mua, ua ʻike ʻia kahi noiʻi cross-sectional.
Ke hoʻohālikelike ʻia i kahi hui makahiki, ʻo nā wahine ma lalo o 46 i hana i ka premenopausal bilateral oophorectomy (PBO) no nā kūlana nonmalignant-me ka ʻole a i ʻole ka hysterectomy-ʻaʻole i hana maikaʻi ʻia ma kahi hoʻokolohua hele wāwae ʻeono minuke i mālama ʻia i loko o kahi keʻena maʻi maʻi maʻi ʻelua mau makahiki ma hope a ua ʻoi aku ka maikaʻi. e loaʻa i nā maʻi mau loa:
Asthma: a i ʻole 1.74 (95% CI 1.03-2.93)
ʻO ka ʻeha ʻeha: a i ʻole 1.64 (95% CI 1.06-2.55)
ʻAi ʻana i ka hiamoe hiamoe: a i ʻole 2.00 (95% CI 1.23-3.26)
Haʻihaʻi: a i ʻole 2.86 (95% CI 1.17-6.98)
"Ke hōʻike nei kēia mau hopena i nā hopena maikaʻi ʻole o ka oophorectomy no nā wahine me nā hōʻailona maikaʻi ʻole a ʻaʻohe ovarian i loaʻa i ka maʻi genetic awelika no ka maʻi kanesa ovarian." ʻO ka lāʻau lapaʻau ma Winston-Salem, NC, ma kahi ʻatikala ma Menopause.He mea koʻikoʻi kēia mau hopena i ka wā e noʻonoʻo ai inā e hana ʻia ka ovariectomy (PBO) a me ka hysterectomy.
ʻO Stephanie Faubion, MD, MBA, ka luna lapaʻau o ka Menopause Society, i'ōleloʻia nā mea i loaʻa, e hilinaʻi ana i ka Tubectomy a me ka Aging Cohort Study-2 (MOA-2) o Mayo Clinic, e hōʻoia i ka pono o nā kauka e hoʻololi i kā lākou mau hana.
"Hoʻohui wale kēia i nā palapala i loaʻa i ka wehe ʻana i nā ovaries i ka wā ʻōpio, ʻoi aku ma lalo o ka makahiki 46, pili i nā hopena olakino maikaʻi ʻole," i haʻi aku ai ʻo Faubion iā MedPage Today.I kēia manawa, manaʻo wau pono mākou e hana. "
ʻO Faubion, ʻo ia hoʻi ka luna o ka Center for Women's Health ma ka Mayo Clinic ma Rochester, Minnesota, akā ʻaʻole i komo i ka noiʻi o kēia manawa, ua ʻōlelo ʻo ka mare ʻana ma hope (nā wahine ma waena o nā makahiki 46 a me 49) ʻaʻole ia he manaʻo maikaʻi," e like me ke aʻo ʻana.I loko o kēia pūʻulu, ua hoʻonui ʻia ka nui o ka maʻi o ka maʻi a me ka apnea hiamoe i hoʻohālikelike ʻia me kā lākou mau hoa pili makahiki, a ua alakaʻi ʻo PBO i ka piʻi ʻana o ka maʻi pulmonary obstructive maʻi i ka cohort holoʻokoʻa.
Ma ka hui PBO, ma kahi o 90 pakeneka i loaʻa i ka hysterectomy, a he 6 pakeneka i loaʻa i ka hysterectomy ma mua o kēlā;i loko o ka pūʻulu kuhikuhi pili makahiki i loaʻa ʻole i ka PBO, 9 pakeneka i loaʻa i kahi hysterectomy.
Ua haʻi ʻo Mielke iā MedPage Today ʻo ka wehe ʻana i nā ovaries i ka wā o ka hysterectomy (ʻo ka lua o ka hana maʻamau no nā wahine) he hana maʻamau ia no nā wahine, ma kahi ʻāpana no ka mea e hoʻopau i ka pilikia o ka maʻi maʻi ovarian.
"Ma ka mōʻaukala," wehewehe ʻo Mielke, "ua manaʻo ʻia i ka wā i wehe ʻia ai ka ʻōpū, ʻaʻole hiki ke hana hou, a no laila ʻaʻole pono e wehe i nā ovaries."Eia nō naʻe, i ka hala ʻana o ka manawa, ʻoi aku ka nui o nā noiʻi i hōʻike ʻia ʻo ka wehe ʻana i nā ovaries ʻelua ma mua o ka menopause kūlohelohe hiki ke loaʻa nā hopena lōʻihi a i ʻole nā hopena lōʻihi o nā maʻi ʻē aʻe.
Inā hoʻoneʻe ʻia nā ovaries ma mua o ka menopause kūlohelohe, ʻōlelo ʻo Milk, "ʻoi aku ka ikaika" e noho nā wahine i ka estrogen therapy a hiki i ka makahiki 50.
Ua ʻike ka poʻe noiʻi i ka noiʻi ʻana i kēia manawa i loko o kahi loiloi kino kanaka piha o nā wahine me ka moʻolelo i kākau ʻia o PBO, aʻo nā haʻawina ʻē aʻe e pili ana i ka PBO a me nā hopena olakino i hilinaʻi nui ʻia i ka hōʻiliʻili passive o nā hopena mai nā moʻolelo olakino, ʻaʻole i hopu i "nā kikowaena kikoʻī. o ka hana kino a i ʻole nā hana ʻē aʻe e pili ana i ka ʻelemakule.
E aʻo i nā kikoʻī
Ua hoʻohana ʻo Mielke a me nā hoa hana i ka ʻikepili mai ka Rochester Epidemiology Project's (REP) Medical Record Linkage System a me ka MOA-2 study, i ʻike i nā wahine ma Olmsted County, Minnesota, i mālama ʻia me PBO no nā kūlana nonmalignant ma waena o 1988 a me 2007 a ʻaʻole i kiʻekiʻe ka pilikia no ka maʻi maʻi ovarian. Ua hoʻohālikelike ʻia nā mea komo MOA-2 me kahi hui kuhikuhi o nā wahine i loaʻa ʻole iā PBO i hui pū ʻia me kahi hui kuhikuhi o nā wahine i loaʻa ʻole iā PBO.
I ka makahiki 2018, i ka wā i hoʻomaka ai ka noiʻi maka-a-maka, ʻo ka hapa nui o ka poʻe i loko o ka PBO a me nā hui kuhikuhi e ola mau ana (91.6% a me 93.1%, kēlā me kēia).
Ua kiʻi ka hui noiʻi i 274 mau wahine ʻōlelo Pelekania mai MOA-2 nāna i mālama i ke kanaka me ka PBO ma hope o ka median o 22 mau makahiki, me 161 mau maʻi i hana mua i ke kaʻina hana (ma mua o ka makahiki 46) (59%) a me 113 mau maʻi. ka mea i hana i ke kaʻina hana lohi (makahiki 46 a hiki i 49) (41%).
Pono ka poʻe i komo i ka makahiki 55 a ʻoi paha ma ke kākau inoa ʻana a ua kāpae ʻia inā hōʻike ʻia ka maʻi maʻi i kā lākou PBO a inā ʻaʻole lākou i ʻike ʻia ma REP i nā makahiki 5 i hala.Ua hoʻohālikelike ʻia lākou i nā makahiki 240 i ka hui kuhikuhi i loaʻa ʻole kahi PBO.
ʻO ka holoʻokoʻa, he 67 mau makahiki ma waena o nā wahine, he 97% -99% keʻokeʻo, a ma kahi o 60% ʻaʻole i puhi.
Ua helu ʻia nā maʻi maʻi e nā moʻolelo olakino.Ma waho aʻe o nā hui i haʻi muaʻia,ʻaʻole i loaʻa i nā mea noiʻi kekahi pilina ma waena o ka PBO a me ka maʻi kanesa, ka maʻi maʻi, ka dementia, ke kiʻekiʻe, ka hyperlipidemia, ka arrhythmia cardiac, ka maʻi, ka thyroid, a me ka maʻi ate, osteoporosis, a iʻole ka hōʻeha ischemic transient.
Hoʻokomo ʻia ka hoʻokolohua kino i nā ana o ka ikaika a me ka neʻe ʻana.Ke hoʻohālikelike ʻia me ka hui kuhikuhi makahiki, ʻoi aku ka kiʻekiʻe o ka nui o ka momona thyroid / pteronavicular i nā wahine i loaʻa i ka PBO a maikaʻi ʻole ka hana ma ka hoʻāʻo hele wāwae 6-minute (-14 mika), akā ʻoi aku ka maikaʻi o nā wahine i loaʻa i ka PBO mua ma ka 6 mau minuke. hōʻike hele wāwae (-18 mika).ʻO nā wāhine o ka pūʻulu PBO hope loa, ua ʻoi aku ka nui o ka nui o ka momona o ka momona, ka lean mass appendicular, a me ka nui o ka mineral iwi spinal i hoʻohālikelike ʻia me ka hui kuhikuhi.
Ua ʻike ʻo Mielke a me nā hoa hana no ka mea he cross-section ka haʻawina, ʻaʻole hiki ke ʻike ʻia ke kumu kumu, a ua ʻōlelo ʻia nā haʻawina longitudinal.Ua ʻike pū lākou he ʻoi aku ka maikaʻi o nā wahine i komo i ke aʻo ʻana ma mua o ka heluna lehulehu a kuhikuhi i ka predominance o nā keʻokeʻo ʻo ia kekahi o nā palena o ka noiʻi.
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Ka manawa hoʻouna: Sep-18-2023